The end of the COVID Public Health Emergency on May 11, 2023 will bring changes to NIH, AHRQ, and NIOSH guidance implemented during the pandemic. Effective for applications submitted on May 25, 2023 and beyond, a one-page update of preliminary data as post-submission material may be submitted only for R01, R03, and R21 applications, as long as the funding opportunity allows submission of preliminary data. The Notice is available here: https://bit.ly/3ZP9no4