The NIH R25 is one of several NIH Resource grants (in this case, the R stands for Resource not Research) that are meant to be used to provide research-related projects or improve infrastructure.
The R25 is meant to increase interest, understanding, and training in biomedical, behavioral, and clinical research. Different ICs use the R25 in a wide variety of ways, from providing hands-on research experiences to holding short courses for skills development. The participants can range from high school students and teachers, to undergraduates, graduate students, postdocs, residents, or early career scientists, depending on the focus of the NOFO.
Because of the breadth of possible activities supported by the various R25s, award budget limits may vary between NOFOs. Also, certain NOFOs for R25s require a letter of intent (LOI) 30 days before the application is due. Additionally, R25 submission deadlines don’t fall on the NIH standard due dates schedule, so be sure to check the NOFO.